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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYFIP1
All Species:
13.64
Human Site:
Y298
Identified Species:
23.08
UniProt:
Q7L576
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L576
NP_001028200.1
1253
145182
Y298
N
L
S
K
I
D
K
Y
F
K
Q
L
Q
V
V
Chimpanzee
Pan troglodytes
XP_001137120
1278
148380
F298
N
L
S
K
I
D
K
F
F
K
Q
L
Q
V
V
Rhesus Macaque
Macaca mulatta
XP_001105005
1359
156392
F379
N
L
S
K
I
D
K
F
F
K
Q
L
Q
V
V
Dog
Lupus familis
XP_536156
1212
140594
Y298
N
L
S
K
I
D
K
Y
F
K
Q
L
Q
V
V
Cat
Felis silvestris
Mouse
Mus musculus
Q7TMB8
1253
145223
Y298
N
L
S
K
I
D
K
Y
F
K
Q
L
Q
V
V
Rat
Rattus norvegicus
NP_001100987
1253
145239
Y298
N
L
S
K
I
D
K
Y
F
K
Q
L
Q
V
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508077
1255
145699
F298
N
L
S
K
I
D
K
F
F
K
Q
L
Q
V
V
Chicken
Gallus gallus
XP_414567
1253
145683
F298
N
L
S
K
I
D
K
F
F
K
Q
L
Q
V
V
Frog
Xenopus laevis
Q6GQD1
1253
145619
F298
N
L
S
K
I
D
K
F
F
K
Q
L
Q
V
V
Zebra Danio
Brachydanio rerio
Q90YM8
1253
145156
F298
N
L
T
K
I
D
K
F
F
K
Q
L
Q
V
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VF87
1291
149242
I298
R
L
D
R
I
D
R
I
F
K
N
L
E
V
V
Honey Bee
Apis mellifera
XP_395632
1292
149877
I299
K
L
D
R
I
D
R
I
F
K
N
L
E
V
V
Nematode Worm
Caenorhab. elegans
O44518
1262
144995
I298
S
I
S
R
L
D
K
I
F
K
T
L
E
V
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q5S2C3
1283
145467
K295
N
R
L
I
N
I
F
K
N
D
P
V
I
P
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.9
81
96
N.A.
99
99.1
N.A.
87.4
87.7
86.9
92.5
N.A.
65.4
67.8
51.7
N.A.
Protein Similarity:
100
92.1
86.9
96.4
N.A.
99.6
99.7
N.A.
93.7
94
93.8
96.9
N.A.
80.4
81.2
70.8
N.A.
P-Site Identity:
100
93.3
93.3
100
N.A.
100
100
N.A.
93.3
93.3
93.3
86.6
N.A.
53.3
53.3
53.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
73.3
73.3
86.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
15
0
0
93
0
0
0
8
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
22
0
0
% E
% Phe:
0
0
0
0
0
0
8
43
93
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
8
86
8
0
22
0
0
0
0
8
0
0
% I
% Lys:
8
0
0
72
0
0
79
8
0
93
0
0
0
0
0
% K
% Leu:
0
86
8
0
8
0
0
0
0
0
0
93
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
79
0
0
0
8
0
0
0
8
0
15
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
72
0
72
0
0
% Q
% Arg:
8
8
0
22
0
0
15
0
0
0
0
0
0
0
0
% R
% Ser:
8
0
72
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
8
0
93
93
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
29
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _